The spine and orthopedic medtech space has been rife with major deals from acquisitions to spinoffs in recent years.

Centinel Spine finished enrollment for a 2-level Investigational Device Exemption trial for the Prodisc C Vivo and Prodisc C SK disc replacement devices, the company said June 13. 

Spinal technology medical device company Mighty Oak Medical has partnered with HP to develop 3D-printed medical models and surgical guides using an HP Jet Fusion 5200, according to a June 12 report from TCT Magazine.

Medtronic's plans to separate its combined patient monitoring and respiratory interventions businesses will likely go forward, Seeking Alpha reported June 12. 

Brian Ipsen, MD, an orthopedic spine surgeon in Galena, Kan., has completed his 300th case using Augmedics' Xvision spine navigation system, according to a June 12 LinkedIn post from the medtech company. 

Themistocles Protopsaltis, MD, recently performed his first DualPortal endoscopic spinal surgery at NYU Langone Health in New York City. 

SurGenTec has earned FDA clearance for its proprietary TiLink-L Sacroiliac Joint Fusion System, which can be implanted from a lateral or posterior/oblique approach and uses unique surface technology to optimize bone growth. 

Armen Khachatryan, MD, of The Disc Replacement Center in Salt Lake City completed the first cases with the Motus lumbar total joint system as part of a clinical trial.

Neuralink, Elon Musk's brain implant company reached a key milestone and was approved by the FDA for human trials.

The Physicians Committee for Responsible Medicine on May 26 released a statement urging Elon Musk and his company Neuralink to pivot clinical trials for a brain implant.

Elon Musk's Neuralink recieved FDA approval for human trials, according to a May 25 tweet.

Medtronic on May 25 posted sales of $31.2 billion for fiscal year 2023 and $8.5 billion in the fourth quarter.

The first cases using Stryker's Q guidance system and cranial guidance software were completed, the company said May 24.

Hoag Spine Center in Newport Beach, Calif. is the first in Orange County to install the EOSedge system for spine imaging, according to a May 24 news release.

Aurora Spine reported a total revenue of $2.96 million in the first quarter of 2023, a 16.7 percent decrease compared to the same period in 2022.

Here are 35 spine and orthopedic medtech companies to follow in 2023.

Here are six spine devices garnering attention from the FDA that Becker's has reported on since May 4:

Centinel Spine in the first quarter of 2023 saw record worldwide motion preservation sales, the devicemaker said May 18.

CTL Amedica's Nitro interbody fusion cage system portfolio was cleared by the FDA, the devicemaker said May 18. 

Since its launch in 2008, Eminent Spine has evolved significantly— having started as a polyetheretherketone (PEEK) interbody spinal fusion devices company that shifted focus to pedicle screws and now specializes in 3D titanium printing technology.