Ronda Stryker, Jon Stryker and Pat Stryker are grandchildren of Homer Stryker, the company's founder, who died in 1980.
Each of the three grandchildren got a stake in the company, helping them amass billions in wealth.
Ronda Stryker, 68, has a net worth of $5.6 billion. She is the only grandchild who works for Stryker, serving as one of its directors and sitting on the board.
Jon Stryker, 64, has a net worth of $3.6 billion. He lives in New York City and works as the president and founder of a human rights philanthropy.
Pat Stryker, 66, has a net worth of $2.6 billion. She works as the founder of a program that supports music, community, global and civic programs.
John Brown, 88, has no familial relation to the Strykers, but he made his $4.6 billion in wealth running the corporation for 32 years. Mr. Brown retired from the company in 2009 but still owns a little more than 5 percent.