The FDA on July 2 granted 510(k) clearance for Spinal Elements' Sapphire X anterior cervical fixation system.

Pacira BioSciences notified DePuy Synthes Sales that its agreement to market and promote Exparel for orthopedic procedures in the U.S. will expire Jan. 2, 2021.

Privately held orthopedic implant company Engage Surgical released a cementless partial knee replacement system July 1, after receiving FDA approval.

Spinal implant developer Xenco Medical on June 30 launched CancelleX, a porous titanium lumbar interbody system.

SeaSpine launched its Mariner MIS and Mariner Outrigger spinal fixation systems June 30.

Medtronic has withdrawn its Infuse Bone Graft/LT-Cage Lumbar Tapered Fusion device from the Australian market as of March 23, according to a statement provided to Becker's Spine Review.

Here's how Medtronic, Stryker and Johnson & Johnson's shares have fluctuated over the last five days.

Spinal device manufacturer CoreLink received FDA 510(k) clearance for its F3D-C2 standalone cervical spine system June 30.

Stryker has extended the offering period of its cash tender offer for all outstanding ordinary shares of Wright Medical Group, a device company focusing on orthopedic extremities and biologics.

Medical device company SpineGuard has completed the first procedures with its DSG Connect system, according to a June 29 announcement.

Medical device company Nexxt Spine is seeking to hire employees across a range of departments, including manufacturing, regulatory, marketing and logistics.

Medtronic Canada has been recognized in the 2020 list of Best Workplaces in Ontario, according to a June 25 announcement.

Medical technology company Brainlab on June 29 acquired Level Ex, a Chicago-based startup that develops video games to improve physicians' clinical skills.

Synthes Gmbh, a Johnson and Johnson medical device company, on June 29 renewed a five-year corporation agreement with the AO Foundation, a global network of surgeons.

German medical technology company Brainlab on June 26 launched Snke OS, a subsidiary focused on developing software to improve surgical navigation.

The Attune Knee system, developed by DePuy Synthes, has been implanted in more than one million patients, according to a June 23 press release.

Here are seven key notes on spine and orthopedic device companies:

Spine-facing medical technology company Carlsmed closed a $2.5 million fundraising round and concurrently made a pair of leadership appointments.

Four device companies that have received or sought financial relief due to the COVID-19 pandemic:

Baltimore-based Johns Hopkins Medicine surgeons used the Augmedics Xvision Spine System surgical guidance system to perform a pair of spine surgeries in early June, making Johns Hopkins the first institution in the U.S. to perform augmented reality spine surgeries.